Powerful antibacterial nanocomposites from <i>Corallina officinalis</i>-mediated nanometals and chitosan nanoparticles against fish-borne pathogens

Abstract The fish-borne zoonotic bacteria may pose a risk to humans; nanobiotechnological techniques could serve as effective solutions for fighting them. direct phycosynthesis of metals’ nanoparticles (NPs), silver (AgNPs), and selenium (SeNPs) using Corallina officinalis extract (CoE) was achieved. construction nanocomposites (NCs) from phycosynthesized NPs nano-chitosan (NCht) also accomplished evaluate these entire compounds/NCs antibacterial amalgams against bacteria, Aeromonas hydrophila , Pseudomonas aeruginosa Salmonella typhimurium Staphylococcus aureus . agents/NCs were characterized assessed. structure interactions chemicals NCs determined infrared analysis. CoE/AgNPs, CoE/SeNPs, NCht, NCht/CoE/AgNPs, NCht/CoE/SeNPs had mean particles’ diameter 5.52, 12.46, 59.81, 64.59, 77.16 nm, respectively, which confirmed by size studies electron microscopy. challenged entirely susceptible the inspected agents, both qualitative quantitative assays; S. more resistant, while A. most sensitive strain. (NCht/CoE/AgNPs NCht/CoE/SeNPs) have utmost bactericidal potentialities, respectively; they exceeded action ampicillin. total distortion, disintegration, lysis treated cells highlighted scanning imaging within 10 h exposure. conjugation CoE-mediated with NCht produced harmless NCs, valid applications remove pathogens biosafe characteristics.